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非精原细胞瘤性睾丸癌的管理:当前治疗方法与未来方向

The management of nonseminomatous testicular cancer: current therapy and future directions.

作者信息

Ostrow S S

出版信息

Am J Med Sci. 1983 Jan-Feb;285(1):24-37. doi: 10.1097/00000441-198301000-00003.

DOI:10.1097/00000441-198301000-00003
PMID:6337490
Abstract

Carcinoma of the testes is the fourth leading cause of death in males between the ages of 15-54, and its incidence may be increasing. Nonseminomatous testicular cancer represents 50% of all testicular tumors. There have been recent advances in diagnosis, staging and therapy of these tumors. Currently, there is a high success rate with platinum containing combination chemotherapy regimens in patients with advanced stages of disease. The article reviews the evolution of successful chemotherapy and the issues of adjuvant therapy for early stage disease, radiation therapy and the role of retroperitoneal lymphadenectomy and surgery following chemotherapy.

摘要

睾丸癌是15至54岁男性中第四大主要死因,其发病率可能正在上升。非精原细胞瘤性睾丸癌占所有睾丸肿瘤的50%。这些肿瘤在诊断、分期和治疗方面最近都有进展。目前,含铂联合化疗方案在晚期疾病患者中成功率很高。本文回顾了成功化疗的演变以及早期疾病辅助治疗、放射治疗以及化疗后腹膜后淋巴结清扫术和手术的作用等问题。

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引用本文的文献

1
Recent trends in mortality due to testicular cancer in Ireland: a comparison with England and Wales.爱尔兰睾丸癌死亡率的近期趋势:与英格兰和威尔士的比较。
J Epidemiol Community Health. 1986 Sep;40(3):218-22. doi: 10.1136/jech.40.3.218.
2
Prognosis of testicular tumour since the introduction of complex therapy.
Int Urol Nephrol. 1989;21(1):81-9. doi: 10.1007/BF02549905.