• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

豚鼠前脑室管膜和室周器官中的5-羟色胺能轴突。一项免疫组织化学研究。

Serotonin axons of the ependyma and circumventricular organs in the forebrain of the guinea pig. An immunohistochemical study.

作者信息

Tramu G, Pillez A, Leonardelli J

出版信息

Cell Tissue Res. 1983;228(2):297-311. doi: 10.1007/BF00204880.

DOI:10.1007/BF00204880
PMID:6337717
Abstract

The distribution of supraependymal nerve fibers (SEF) containing serotonin (5-HT) was investigated immunohistochemically in the forebrain of the guinea pig. The highest densities of immunoreactive axons were found in the pars centralis and the inferior horn of the lateral ventricle and also in the superior part of the third ventricle. Because of the special development of the choroid plexus in these ventricular regions, it is suggested that 5-HT SEF might be involved in the regulation of the composition of the cerebrospinal fluid. The ependyma lining the circumventricular organs located in the forebrain, was not observed to receive a significant 5-HT-SEF innervation. In the pituitary gland, a loose but constant network of 5-HT axons, resembling those which course in the anterobasal hypothalamus, arcuate nucleus and internal layer of the median eminence, was observed in the neural lobe. In the epiphysis, immunoreactive 5-HT was detected in all pinealocytes (the entire cell was filled with reaction product) and in fibers running between them.

摘要

采用免疫组织化学方法研究了豚鼠前脑中含5-羟色胺（5-HT）的室管膜上神经纤维（SEF）的分布。在侧脑室中央部和下角以及第三脑室上部发现免疫反应性轴突密度最高。由于这些脑室区域脉络丛的特殊发育，提示5-HT SEF可能参与脑脊液成分的调节。未观察到位于前脑的室周器官内衬的室管膜接受显著的5-HT-SEF神经支配。在垂体神经叶中，观察到一个松散但恒定的5-HT轴突网络，类似于在前基底下丘脑、弓状核和正中隆起内层中走行的网络。在松果体中，在所有松果体细胞（整个细胞充满反应产物）及其间走行的纤维中检测到免疫反应性5-HT。

相似文献

1
Serotonin axons of the ependyma and circumventricular organs in the forebrain of the guinea pig. An immunohistochemical study.豚鼠前脑室管膜和室周器官中的5-羟色胺能轴突。一项免疫组织化学研究。
Cell Tissue Res. 1983;228(2):297-311. doi: 10.1007/BF00204880.
2
Localization of immunoreactive prolactin in ependyma and circumventricular organs of rat brain.免疫反应性催乳素在大鼠脑的室管膜和室周器官中的定位。
Cell Tissue Res. 1982;225(1):79-93. doi: 10.1007/BF00216220.
3
Serotonin distribution in the circumventricular organs of the rat. An immunohistochemical study.大鼠室周器官中5-羟色胺的分布。一项免疫组织化学研究。
Anat Embryol (Berl). 1983;167(3):311-9. doi: 10.1007/BF00315669.
4
Localization of serotonin in the hypothalamus and the mesencephalon of the guinea-pig. An immunohistochemical study using monoclonal antibodies.
Cell Tissue Res. 1985;240(3):711-21. doi: 10.1007/BF00216360.
5
Immunohistochemical detection of growth hormone-release inhibiting hormone (somatostatin) in the guinea-pig brain.豚鼠脑中生长抑素（促生长激素释放抑制激素）的免疫组织化学检测
Cell Tissue Res. 1975 Aug 25;161(3):385-92. doi: 10.1007/BF00220006.
6
CRF-immunoreactive nerve fibers in the circumventricular organs of the monkey, Macaca fuscata.猕猴（食蟹猴）室周器官中促肾上腺皮质激素释放因子免疫反应性神经纤维。
Cell Tissue Res. 1983;232(3):679-83. doi: 10.1007/BF00216438.
7
Immunohistochemical localization of vasoactive intestinal peptide (VIP) in the circumventricular organs of the rat.血管活性肠肽（VIP）在大鼠室周器官中的免疫组织化学定位。
Cell Tissue Res. 1989 Feb;255(2):307-13. doi: 10.1007/BF00224113.
8
A survey of occurrence of about seventeen circumventricular organs in brains of various vertebrates with special reference to lower groups.对各种脊椎动物大脑中约十七个室周器官的出现情况进行的调查，特别关注较低等的类群。
J Hirnforsch. 1986;27(4):441-70.
9
Central innervation of the rat ependyma and subcommissural organ with special reference to ascending serotoninergic projections from the raphe nuclei.大鼠室管膜和连合下器官的中枢神经支配，特别提及中缝核的5-羟色胺能上行投射
J Comp Neurol. 1997 Aug 11;384(4):556-68.
10
Heterogeneous occurrence of aquaporin-4 in the ependyma and in the circumventricular organs in rat and chicken.水通道蛋白-4在大鼠和鸡的室管膜及室周器官中的异质性分布。
Anat Embryol (Berl). 2006 Mar;211(2):155-72. doi: 10.1007/s00429-005-0067-8. Epub 2006 Jan 17.

引用本文的文献

1
History of research concerning the ependyma: a view from inside the human brain.关于室管膜的研究历史：来自人脑内部的视角。
Front Cell Neurosci. 2024 Jan 8;17:1320369. doi: 10.3389/fncel.2023.1320369. eCollection 2023.
2
Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis.5-HT 在肌萎缩侧索硬化症 G93A 小鼠模型产前脊髓运动神经元氯离子稳态失调中的作用。
Int J Mol Sci. 2020 Feb 7;21(3):1107. doi: 10.3390/ijms21031107.
3
The neural milieu of the developing choroid plexus: neural stem cells, neurons and innervation.

本文引用的文献

1
EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.中枢神经系统中含单胺神经元存在的证据。I. 脑干神经元细胞体中单胺的证实。
Acta Physiol Scand Suppl. 1964:SUPPL 232:1-55.
2
Supraependymal nerve fibres in human brain: correlative transmission and scanning electron microscopical and fluorencence histochemical studies.人类大脑室管膜上神经纤维：相关的透射及扫描电子显微镜和荧光组织化学研究
Neuroscience. 1980;5(8):1489-502. doi: 10.1016/0306-4522(80)90011-1.
3
Serotonin and the regulation of pituitary hormone secretion and of neuroendocrine rhythms.
发育中的脉络丛的神经微环境：神经干细胞、神经元与神经支配。
Front Neurosci. 2015 Mar 31;9:103. doi: 10.3389/fnins.2015.00103. eCollection 2015.
4
Ontogenic changes of the spinal GABAergic cell population are controlled by the serotonin (5-HT) system: implication of 5-HT1 receptor family.脊髓GABA能细胞群的个体发生变化受5-羟色胺（5-HT）系统调控：5-HT1受体家族的作用
J Neurosci. 2005 Sep 21;25(38):8714-24. doi: 10.1523/JNEUROSCI.2398-05.2005.
5
Descending 5-hydroxytryptamine raphe inputs repress the expression of serotonergic neurons and slow the maturation of inhibitory systems in mouse embryonic spinal cord.下行的5-羟色胺中缝输入抑制血清素能神经元的表达，并减缓小鼠胚胎脊髓中抑制系统的成熟。
J Neurosci. 2002 Apr 1;22(7):2598-606. doi: 10.1523/JNEUROSCI.22-07-02598.2002.
6
Central control of blood pressure by nitrergic mechanisms in organum vasculosum laminae terminalis of rat brain.大鼠脑终板血管器中一氧化氮能机制对血压的中枢控制。
Br J Pharmacol. 1999 Jul;127(6):1511-7. doi: 10.1038/sj.bjp.0702699.
7
distribution of monoamine-containing nerve fibers in the pineal organ of untreated and sympathectomized dogs. Fluorescence- and immunohistochemical studies.未处理和交感神经切除犬松果体中含单胺神经纤维的分布。荧光和免疫组织化学研究。
Cell Tissue Res. 1983;234(3):519-31. doi: 10.1007/BF00218648.
8
Serotonin distribution in the circumventricular organs of the rat. An immunohistochemical study.大鼠室周器官中5-羟色胺的分布。一项免疫组织化学研究。
Anat Embryol (Berl). 1983;167(3):311-9. doi: 10.1007/BF00315669.
9
Immunohistochemical demonstration of serotonergic and peptidergic nerve fibers in the subcommissural organ of the dog.犬连合下器官中5-羟色胺能和肽能神经纤维的免疫组织化学显示
Cell Tissue Res. 1987 May;248(2):287-95. doi: 10.1007/BF00218195.
10
Anti-5-hydroxytryptamine antibodies: studies on their cross-reactivity in vitro and their immunohistochemical specificity.抗5-羟色胺抗体：关于其体外交叉反应性及免疫组织化学特异性的研究
Exp Brain Res. 1986;63(3):627-38. doi: 10.1007/BF00237485.
血清素与垂体激素分泌及神经内分泌节律的调节
J Physiol (Paris). 1981;77(2-3):489-96.
4
Pools of serotonin in the pineal gland of the mouse: the mammalian pinealocyte as a component of the diffuse neuroendocrine system.小鼠松果体中的5-羟色胺池：作为弥散神经内分泌系统组成部分的哺乳动物松果体细胞。
Cell Tissue Res. 1980;213(2):273-91. doi: 10.1007/BF00234787.
5
Immunohistochemical demonstration of the distribution of serotonin neurons in the brainstem of the rat and cat.大鼠和猫脑干中5-羟色胺神经元分布的免疫组织化学显示。
Cell Tissue Res. 1982;224(2):247-67. doi: 10.1007/BF00216872.
6
Demonstration of supra-ependymal 5-HT nerve fibres in human brain and their immunohistochemical identification in rat brain.人脑中室管膜上5-羟色胺神经纤维的显示及其在大鼠脑中的免疫组织化学鉴定。
J Physiol (Paris). 1981;77(2-3):219-24.
7
Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.大鼠中枢神经系统中5-羟色胺免疫反应性的分布——细胞体和终末
Neuroscience. 1981;6(4):557-618. doi: 10.1016/0306-4522(81)90146-9.
8
The serotonin innervation of the cerebral cortex in the rat--an immunohistochemical analysis.大鼠大脑皮质的5-羟色胺神经支配——免疫组织化学分析
Neuroscience. 1980;5(2):207-27. doi: 10.1016/0306-4522(80)90099-8.
9
Responses of MSH and prolactin cells to 5-hydroxytryptophan (5-HTP) in amphibians and teleosts.两栖动物和硬骨鱼中促黑素细胞和催乳素细胞对5-羟色氨酸（5-HTP）的反应。
Cell Tissue Res. 1980;207(3):377-85. doi: 10.1007/BF00224614.
10
The distribution and orientation of serotonin fibers in the entorhinal and other retrohippocampal areas. An immunohistochemical study with anti-serotonin antibodies in the rats brain.
Anat Embryol (Berl). 1981;161(3):237-64. doi: 10.1007/BF00301824.