与福氏志贺菌感染相关的暴发性脑病
Fulminating encephalopathy associated with Shigella flexneri infection.
作者信息
Sandyk R, Brennan M J
出版信息
Arch Dis Child. 1983 Jan;58(1):70-1. doi: 10.1136/adc.58.1.70.
Abstract
Three cases of rapidly fatal encephalopathy associated with Shigella flexneri infection are reported. There was a lack of severe intestinal involvement and absence of metabolic derangement. In all 3 patients, areas of necrosis were present throughout the brains; and in one case pontine haemorrhages and demyelination were seen. This report supports the evidence of a particular neurotoxic effect in shigellosis.
摘要
报告了3例与福氏志贺菌感染相关的快速致死性脑病病例。这些病例缺乏严重的肠道受累情况且不存在代谢紊乱。所有3例患者的整个大脑均出现坏死区域；其中1例可见脑桥出血和脱髓鞘。本报告支持志贺菌病存在特定神经毒性作用的证据。
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本文引用的文献
1
The febrile convulsion in shigellosis.志贺菌病中的热性惊厥。
N Engl J Med. 1958 Mar 13;258(11):520-6. doi: 10.1056/NEJM195803132581102.
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The occurrence of convulsions in children with Shigella gastroenteritis.志贺氏菌性肠胃炎患儿惊厥的发生情况。
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