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High-dose melphalan and autologous bone marrow transplant for relapsed acute leukaemia.

作者信息

Maraninchi D, Abecasis M, Gastaut J A, Sebahoun G, Cahn J Y, Hervé P, Novakovitch G, Carcassonne Y

出版信息

Cancer Chemother Pharmacol. 1983;10(2):109-11. doi: 10.1007/BF00446220.

DOI:10.1007/BF00446220
PMID:6339094
Abstract

Seven patients with relapsed acute leukaemia were treated with high-dose melphalan (HDM) followed by the infusion of autologous cryopreserved remission marrow. Toxicity was minimal and all seven patients had a complete response. Four patients are still in unmaintained remission at 14, 13, 10, and 3 months, the first two having received a second course of HDM to consolidate the result. The role of HDM as a form of intensification therapy for patients with acute myeloid leukaemia in first remission should be investigated.

摘要

相似文献

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High-dose melphalan and autologous bone marrow transplant for relapsed acute leukaemia.
Cancer Chemother Pharmacol. 1983;10(2):109-11. doi: 10.1007/BF00446220.
2
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Treatment of Ewing's sarcoma with high-dose melphalan and autologous bone marrow transplantation.大剂量美法仑和自体骨髓移植治疗尤因肉瘤。
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Autologous bone marrow transplantation for acute myeloid leukaemia in children using total body irradiation and melphalan as conditioning regimen.
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2
Autologous bone marrow transplantation for acute leukemia using transplant chemopurified with metabolite of oxazaphosphorines (ASTA Z 7557, INN mafosfamide). First clinical results.使用经氧氮磷啶类代谢物（ASTA Z 7557，国际非专利药品名称美法仑）化学净化的移植方法进行急性白血病自体骨髓移植。初步临床结果。
Invest New Drugs. 1984;2(2):245-52. doi: 10.1007/BF00232359.
3

本文引用的文献

1
4'-(9-Acridinylamino) methanesulfon-m-anisidide (AMSA): a new drug effective in the treatment of adult acute leukemia.
Ann Intern Med. 1980 Jul;93(1):17-21. doi: 10.7326/0003-4819-93-1-17.
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High dose cytosine arabinoside (HDARAC) in refractory acute leukemia.高剂量阿糖胞苷治疗难治性急性白血病
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Marrow autotransplantation accelerates haematological recovery in patients with malignant melanoma treated with high-dose melphalan.骨髓自体移植可加速接受大剂量美法仑治疗的恶性黑色素瘤患者的血液学恢复。
Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow.
维拉帕米增强美法仑对小鼠纤维肉瘤和骨髓的细胞毒性及细胞摄取。
Br J Cancer. 1985 Dec;52(6):813-22. doi: 10.1038/bjc.1985.264.
4
Phase-I-II study of high-dose melphalan and autologous marrow transplantation in adult patients with poor-risk non-Hodgkin's lymphomas.高剂量美法仑与自体骨髓移植用于高危非霍奇金淋巴瘤成年患者的I-II期研究
Cancer Chemother Pharmacol. 1985;14(3):216-21. doi: 10.1007/BF00258119.
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Treatment of advanced neuroblastoma with high-dose melphalan and autologous bone marrow transplantation.大剂量美法仑联合自体骨髓移植治疗晚期神经母细胞瘤
Cancer Chemother Pharmacol. 1986;16(2):165-9. doi: 10.1007/BF00256169.
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Intensive chemotherapy with high doses of BCNU, etoposide, cytosine arabinoside, and melphalan (BEAM) followed by autologous bone marrow transplantation: toxicity and antitumor activity in 26 patients with poor-risk malignancies.采用大剂量卡莫司汀、依托泊苷、阿糖胞苷和美法仑（BEAM）进行强化化疗，随后进行自体骨髓移植：26例高危恶性肿瘤患者的毒性和抗肿瘤活性
Cancer Chemother Pharmacol. 1988;22(3):256-62. doi: 10.1007/BF00273421.
Br J Cancer. 1979 Jul;40(1):72-80. doi: 10.1038/bjc.1979.142.
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Autologous bone-marrow transplantation in relapsed adult acute leukaemia.复发的成年急性白血病患者的自体骨髓移植
Lancet. 1979 Mar 10;1(8115):514-7. doi: 10.1016/s0140-6736(79)90943-7.
5
Vinblastine, 5-azacytidine, and VP-16-213 therapy for previously treated patients with acute nonlymphocytic leukemia.长春花碱、5-氮杂胞苷和依托泊苷对既往接受过治疗的急性非淋巴细胞白血病患者的治疗
Cancer Treat Rep. 1977 Nov;61(8):1599-602.
6
5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia.5-氮杂胞苷。一种对急性髓性白血病有效的新型抗癌药物。
Ann Intern Med. 1976 Aug;85(2):237-45. doi: 10.7326/0003-4819-85-2-237.