Solberg L E, Nissen R G, Vlietstra R E, Callahan J A
Mayo Clin Proc. 1978 Apr;53(4):256-9.
A patient with frequent attacks of Prinzmetal's variant angina complicated by ventricular tachycardia and ventricular fibrillation is described in whom these episodes persisted daily during 4 weeks of hospital observation in spite of treatment with nitrates, alpha-adrenergic-blocking drugs, and anticholinergic agents. The oral administration of verapamil, an investigational vasodilator drug, led to prompt and complete resolution of the attacks.
本文描述了一名患有普林兹金属变异型心绞痛且频繁发作,并伴有室性心动过速和心室颤动的患者。尽管使用了硝酸盐类药物、α-肾上腺素能阻滞剂和抗胆碱能药物进行治疗,但在住院观察的4周时间里,这些发作仍每天持续。口服一种正在研究的血管扩张剂维拉帕米后,发作迅速且完全得到缓解。