Sheth N K, Post G T, Wisniewski T R, Uttech B V
J Clin Microbiol. 1983 Feb;17(2):377-9. doi: 10.1128/jcm.17.2.377-379.1983.
A total of 197 multidose injectable vials were collected from 10 different nursing stations and evaluated for sterility. Experimental contamination studies were undertaken, and the cost-effectiveness of multidose vials was compared with that of single-dose vials. Our results showed that bacterial contamination of multidose injectable vials was not a significant hazard; in addition, contrary to common belief, the use of multidose vials was not always successful as a cost-containment measure.
从10个不同的护理站收集了总共197个多剂量注射瓶,并对其无菌性进行评估。开展了实验性污染研究,并将多剂量瓶与单剂量瓶的成本效益进行比较。我们的结果表明,多剂量注射瓶的细菌污染并非重大风险;此外,与普遍看法相反,使用多剂量瓶作为成本控制措施并非总是成功的。