Nasmyth K
Nature. 1983 Apr 21;302(5910):670-6. doi: 10.1038/302670a0.
Mating type interconversion has a precise lineage which serves to minimize the time taken for yeast cells to achieve the diploid state. The HO gene either encodes or regulates an endonuclease which initiates the interconversion process. Expression of this gene is switched on during the G1 phase of mother cells and not at all during the cell cycle of their daughters. This behaviour can explain what is known about the lineage.
交配型相互转换有一个精确的谱系，其作用是将酵母细胞达到二倍体状态所需的时间减至最短。HO基因要么编码一种内切核酸酶，要么对其进行调控，该内切核酸酶启动相互转换过程。该基因的表达在母细胞的G1期开启，而在子细胞的细胞周期中完全不开启。这种行为可以解释关于该谱系的已知情况。
