Gröndahl K, Gröndahl H G, Webber R L
Oral Surg Oral Med Oral Pathol. 1983 Mar;55(3):313-8. doi: 10.1016/0030-4220(83)90334-1.
Standardized radiographs were obtained of the molar and premolar areas of dry human mandibles before and after small lesions were induced in the alveolar bone crest. The radiographs were digitized, and various amounts of random noise were added to simulate images produced by more efficient, low-radiation-dose systems. Subtraction images were produced from these noise-degraded radiographs. The diagnostic performance of human observers from these images was then compared with that obtained from both subtraction images made from nondegraded radiographs and from the original, conventional images. The diagnostic accuracy obtained with subtraction images, even if they were made from severely noise-degraded images, was equal or superior to that obtained with the conventional radiographs. This indicates that structured noise, which is reduced by the subtraction procedure, is a predominant, limiting factor in the diagnosis of small periodontal bone lesions. It also suggests that the application of a subtraction technique for the detection of such changes occurring over a period of time can make possible the use of significantly faster imaging systems than those currently employed.
在牙槽嵴诱导产生小病变之前和之后,获取干燥人下颌骨磨牙和前磨牙区域的标准化X光片。将X光片数字化,并添加各种随机噪声以模拟由更高效、低辐射剂量系统产生的图像。从这些噪声退化的X光片中生成减影图像。然后将人类观察者从这些图像中获得的诊断性能与从未退化X光片制成的减影图像和原始传统图像中获得的诊断性能进行比较。即使减影图像是由严重噪声退化的图像制成的,其获得的诊断准确性也与传统X光片相当或更高。这表明通过减法程序减少的结构化噪声是诊断小牙周骨病变的主要限制因素。这也表明,应用减法技术来检测一段时间内发生的此类变化,可以使用比目前使用的成像系统显著更快的成像系统。