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糖尿病母亲、胎儿及新生儿的钙代谢

Calcium metabolism in diabetic mother, fetus, and newborn infant.

作者信息

Cruikshank D P, Pitkin R M, Varner M W, Williams G A, Hargis G K

出版信息

Am J Obstet Gynecol. 1983 Apr 15;145(8):1010-6. doi: 10.1016/0002-9378(83)90858-x.

DOI:10.1016/0002-9378(83)90858-x
PMID:6340509
Abstract

Peripheral blood levels of the minerals and hormones involved in calcium homeostasis were measured in insulin-dependent diabetic patients at delivery, and in umbilical arterial and venous blood. The minerals were also measured in neonatal blood at 24 hours of age. Insulin-dependent diabetic patients at delivery have depressed serum levels of parathyroid hormone, although serum total and ionized calcium levels are not different from those of nondiabetic patients. Fetuses of diabetic mothers are hypocalcemic and have reduced parathyroid hormone levels. Infants of diabetic mothers demonstrate early neonatal hypocalcemia. No differences between diabetic and control patients could be demonstrated in terms of calcitonin or phosphorus levels, in either mother, fetus, or neonate.

摘要

对胰岛素依赖型糖尿病患者分娩时的外周血以及脐动脉血和脐静脉血中参与钙稳态的矿物质和激素水平进行了测量。还对出生24小时的新生儿血液中的矿物质进行了测量。胰岛素依赖型糖尿病患者分娩时血清甲状旁腺激素水平降低,尽管血清总钙和离子钙水平与非糖尿病患者并无差异。糖尿病母亲的胎儿存在低钙血症且甲状旁腺激素水平降低。糖尿病母亲的婴儿表现出早期新生儿低钙血症。在母亲、胎儿或新生儿的降钙素或磷水平方面,糖尿病患者与对照患者之间未显示出差异。

相似文献

1
Calcium metabolism in diabetic mother, fetus, and newborn infant.糖尿病母亲、胎儿及新生儿的钙代谢
Am J Obstet Gynecol. 1983 Apr 15;145(8):1010-6. doi: 10.1016/0002-9378(83)90858-x.
2
Calcium metabolism in newborn infants. The interrelationship of parathyroid function and calcium, magnesium, and phosphorus metabolism in normal, "sick," and hypocalcemic newborns.新生儿的钙代谢。正常、“患病”及低钙血症新生儿甲状旁腺功能与钙、镁、磷代谢的相互关系。
J Clin Invest. 1974 Aug;54(2):287-96. doi: 10.1172/JCI107764.
3
Calcitonin and parathyroid hormone--relation to early neonatal hypocalcemia in infants of diabetic mothers.降钙素与甲状旁腺激素——与糖尿病母亲所生婴儿早期新生儿低钙血症的关系
Biol Neonate. 1974;24(1):151-60. doi: 10.1159/000240646.
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Calcium metabolism in pregnancy and the perinatal period: a review.孕期及围产期的钙代谢:综述
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Parathyroid function in infants of diabetic mothers.糖尿病母亲所生婴儿的甲状旁腺功能
J Pediatr. 1975 Mar;86(3):399-404. doi: 10.1016/s0022-3476(75)80970-x.
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Calcium metabolism in the hypertensive mother, fetus, and newborn infant.高血压母亲、胎儿及新生儿的钙代谢
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[Calcium homeostasis in the newborn infant].[新生儿的钙稳态]
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Altered maternal calcium homeostasis in diabetic pregnancy.
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Hypocalcemia in infants of diabetic mothers. Studies in calcium, phosphorus, and magnesium metabolism and parathormone responsiveness.糖尿病母亲婴儿的低钙血症。钙、磷和镁代谢及甲状旁腺素反应性的研究。
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Prevention of early neonatal hypocalcemia in low birth weight infants with continuous calcium infusion: effect on serum calcium, phosphorus, magnesium, and circulating immunoreactive parathyroid hormone and calcitonin.持续输注钙剂预防低出生体重儿早期新生儿低钙血症:对血清钙、磷、镁以及循环免疫反应性甲状旁腺激素和降钙素的影响
Pediatr Res. 1977 Dec;11(12):1180-5. doi: 10.1203/00006450-197712000-00003.

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