Piton J L, Alibeu C, Renversez J C, Chenais F, Tournoud A, Dodelier C, Phelip X, Cabanel G
Rev Rhum Mal Osteoartic. 1983 Jan;50(1):9-18.
The detection of serum immune complexes in cases of rheumatoid arthritis (RA) was performed using four different detection techniques: cryoglobuline (CG), the polyethylene glycol C1q test (PEGC1q), the 125I labelled C1q test (C1qBA) and the detection of anticomplement power (ACP). CG, PEGC1q, and C1qBA are more often positive in cases of sero-positive RA than in sero-negative RA (p less than 0,001 for each test). There are significant and relatively concordant correlations between the positivity of these three tests and certain clinical and laboratory parameters in particular, the level of rheumatoid factor (p less than 0,001) and the presence of extra-articular manifestations. When ACP is found in cases of RA of recent onset, it is associated, in sero-positive cases of RA, with the presence of immune complexes and a more severe form of the disease.
采用四种不同检测技术对类风湿关节炎（RA）患者血清免疫复合物进行检测：冷球蛋白（CG）、聚乙二醇C1q试验（PEGC1q）、125I标记C1q试验（C1qBA）和抗补体活性（ACP）检测。CG、PEGC1q和C1qBA在血清阳性RA患者中比血清阴性RA患者更常呈阳性（每项试验p均小于0.001）。这三项试验的阳性结果与某些临床和实验室参数之间存在显著且相对一致的相关性，尤其是类风湿因子水平（p小于0.001）和关节外表现的存在。在近期发病的RA患者中发现ACP时，在血清阳性的RA病例中，它与免疫复合物的存在以及更严重的疾病形式相关。
