Hironaga M, Ikeda R, Fukazawa Y, Watanabe S
Sabouraudia. 1983 Mar;21(1):73-8.
Thirty-two isolates of Cryptococcus neoformans from patients and one from the wild obtained in Japan were characterized for their serotype, self-fertility, and mating behaviour by crossing them with two mating types of Filobasidiella neoformans var. neoformans and F. neoformans var. bacillispora. Of the 32 isolates from patients, 31 were of serotype A and the remaining one was of serotype D. Although these 32 isolates were all self-sterile, 23 serotype A and one serotype D isolates produced a complete sexual state when mixed with the alpha mating type of F. neoformans var. neoformans. The one natural isolate was of serotype A-D and self-fertile. The Japanese clinical isolates of C. neoformans appear to be predominantly serotype A and alpha mating type of F. neoformans var. neoformans as is the case in the U.S.A.
从日本患者身上获取的32株新型隐球菌分离株以及1株从野外获取的分离株，通过与新型隐球酵母变种新型隐球酵母和新型隐球酵母变种芽殖隐球酵母的两种交配型进行杂交，对其血清型、自育性和交配行为进行了鉴定。在32株来自患者的分离株中，31株为A血清型，其余1株为D血清型。尽管这32株分离株均为自交不育，但当与新型隐球酵母变种新型隐球酵母的α交配型混合时，23株A血清型和1株D血清型分离株产生了完整的有性状态。1株天然分离株为A-D血清型且自育。与美国的情况一样，日本新型隐球菌临床分离株似乎主要为A血清型和新型隐球酵母变种新型隐球酵母的α交配型。
