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[采用局部注射奥古蛋白治疗肱骨外上髁炎(双盲研究)]

[Treatment of epicondylitis with locally injected orgotein (double blind study)].

作者信息

Müller U, Moll G

出版信息

Z Rheumatol. 1983 Jan-Feb;42(1):21-4.

PMID:6342295
Abstract

The efficacy of locally injected orgotein in epicondylitis was investigated in a double-blind clinical trial. The results of the previously used method of treatment--injection with procaine hydrochloride--were applied as a comparison. In nearly all cases of acute epicondylitis, improvement was seen after orgotein injections. More than 70% of these patients were symptom-free 6 weeks after beginning therapy, a result significantly superior to that of the compared method. Both regimens produced distinctly less favorable results in chronic epicondylitis. In acute epicondylitis orgotein may be regarded as an alternative to the more common and potentially risky corticoid therapy.

摘要

在一项双盲临床试验中研究了局部注射奥古蛋白治疗上髁炎的疗效。将先前使用的治疗方法(注射盐酸普鲁卡因)的结果作为对照。在几乎所有急性上髁炎病例中,注射奥古蛋白后病情均有改善。这些患者中超过70%在开始治疗6周后症状消失,这一结果明显优于对照方法。两种治疗方案在慢性上髁炎中产生的效果明显较差。在急性上髁炎中,奥古蛋白可被视为更常用且有潜在风险的皮质类固醇疗法的替代方法。

相似文献

1
[Treatment of epicondylitis with locally injected orgotein (double blind study)].[采用局部注射奥古蛋白治疗肱骨外上髁炎(双盲研究)]
Z Rheumatol. 1983 Jan-Feb;42(1):21-4.
2
Intra-articular orgotein therapy in osteoarthritis of the knee. A double-blind, placebo-controlled trial.膝关节骨关节炎的关节内奥古蛋白治疗。一项双盲、安慰剂对照试验。
Arzneimittelforschung. 1983;33(8):1199-203.
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Orgotein in osteoarthritis of the knee joint.奥古蛋白治疗膝关节骨关节炎
Eur J Rheumatol Inflamm. 1981;4(2):212-8.
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Intrasynovial orgotein therapy in rheumatoid arthritis.类风湿关节炎的滑膜内骨瓜提取物治疗
Lancet. 1981 May 9;1(8228):1015-7. doi: 10.1016/s0140-6736(81)92185-1.
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Orgotein in equine navicular disease: a double blind study.有机金属蛋白酶治疗马舟状骨病:一项双盲研究。
J Am Vet Med Assoc. 1979 Feb 1;174(3):261-4.
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Clinical comparison of orgotein and methylprednisolone acetate in the treatment of osteoarthrosis of the knee joint.奥古蛋白与醋酸甲基泼尼松龙治疗膝关节骨关节炎的临床比较
Scand J Rheumatol. 1984;13(2):108-12. doi: 10.3109/03009748409100372.
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Effect of intra-articular orgotein versus a corticosteroid on rheumatoid arthritis of the knees.关节内注射奥古蛋白与皮质类固醇对膝关节类风湿关节炎的疗效比较
Am J Med. 1983 Jan;74(1):124-8. doi: 10.1016/0002-9343(83)91128-2.
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Orgotein efficacy in ameliorating side effects due to radiation therapy.超氧化物歧化酶在减轻放疗副作用方面的疗效。
Eur J Rheumatol Inflamm. 1981;4(2):228-36.
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[Intra-articular therapy with superoxide dismutase (orgotein) or cortisone in rheumatoid and arthritic inflammatory finger joint lesions].[超氧化物歧化酶(奥古蛋白)或可的松关节内注射治疗类风湿性和关节炎性手指关节病变]
Handchir Mikrochir Plast Chir. 1984 Mar;16(1):59-63.
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[Evaluation of the efficacy of orgotein in a series of patients with hydrarthrosis of the knee].[对一系列膝关节积水患者使用奥古蛋白的疗效评估]
Minerva Med. 1986 May 19;77(21):947-51.

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Corticosteroid injections for lateral epicondylitis: a systematic overview.
皮质类固醇注射治疗外侧上髁炎:系统综述
Br J Gen Pract. 1996 Apr;46(405):209-16.
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Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes.用于治疗的超氧化物歧化酶:临床经验、困境与希望
Mol Cell Biochem. 1988 Dec;84(2):123-31. doi: 10.1007/BF00421046.