Huland H, Bischoff K
J Urol. 1983 May;129(5):925-8. doi: 10.1016/s0022-5347(17)52460-x.
Renograms were obtained immediately after transplantation and repeated every other day beginning 4 days after renal transplantation. In 31 of 32 biopsy-proved acute rejection crises a flattening of phase II (secretion phase) of the renogram occurred. Of the 32 renogram changes 7 were the only signs of rejection at the time of renography. This finding confirms our previous impression based on 116 rejection episodes (diagnosed according to clinical symptoms and response to therapy) that phase II alteration in serial renograms is a sensitive and probably specific sign of rejection. Because this simple method to monitor renal transplantation is not invasive, can be done at the bedside, and gives immediate and easily interpreted results repeated renography is recommended as the basic screening method. Renography is helpful especially in patients with acute tubular necrosis after renal transplantation. The need for more invasive diagnostic procedures, such as renal biopsy and angiography, can be shown by such renograms, although this has occurred rarely in our experience.
移植后立即进行肾图检查，并在肾移植后4天开始每隔一天重复检查一次。在32例经活检证实的急性排斥反应危机中，有31例肾图的II期（分泌期）变平。在32次肾图变化中，有7次是肾图检查时唯一的排斥迹象。这一发现证实了我们之前基于116次排斥反应发作（根据临床症状和治疗反应诊断）得出的印象，即系列肾图中的II期改变是排斥反应的一个敏感且可能具有特异性的迹象。由于这种监测肾移植的简单方法是非侵入性的，可以在床边进行，并且能立即给出易于解读的结果，因此建议重复进行肾图检查作为基本的筛查方法。肾图检查尤其有助于肾移植后发生急性肾小管坏死的患者。通过这样的肾图可以显示出进行更具侵入性的诊断程序（如肾活检和血管造影）的必要性，尽管在我们的经验中这种情况很少发生。
