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[移植皮瓣再致敏的功能与形态学研究]

[Functional and morphological study of the resensitization of transplanted skin flaps].

作者信息

Zocchi M, Teich-Alasia S, Stella M

出版信息

Rev Stomatol Chir Maxillofac. 1983;84(2):85-92.

PMID:6344186
Abstract

A study was conducted to assess sensory function in skin grafts, its effectiveness being an essential condition for ensuring coverage of loss of substance and total functional recovery of the transplanted skin. Morphological and structural criteria to identify cutaneous sensory receptors were established, and data related to their functional activity obtained following an exhaustive literature review. Clinical studies from 1960, employing conventional tests of responses to stimuli, have demonstrated that sensory recovery in transplanted flaps is strictly proportional to that which existed previously. More recent studies have involved equipment to apply stimuli and record responses providing objective assessment of tactile, pain, and thermal sensitivities. Histologic examinations were also performed to try to obtain morphological confirmation o results from the exposed clinical methods. Analysis of a selection of clinical cases studied has demonstrated that more marked recovery of sensory function in transplanted flaps is related to histological evidence of a greater density of regenerated nerve endings.

摘要

开展了一项研究以评估皮肤移植中的感觉功能,其有效性是确保覆盖组织缺损和移植皮肤完全功能恢复的必要条件。建立了识别皮肤感觉受体的形态学和结构标准,并在详尽的文献综述后获得了与其功能活动相关的数据。1960年的临床研究采用了对刺激反应的传统测试,结果表明移植皮瓣的感觉恢复与之前存在的情况严格成正比。最近的研究涉及应用刺激和记录反应的设备,以提供对触觉、疼痛和热敏感性的客观评估。还进行了组织学检查,试图从公开的临床方法中获得结果的形态学证实。对所选研究临床病例的分析表明,移植皮瓣中感觉功能更明显的恢复与再生神经末梢密度更高的组织学证据有关。

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