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[免疫荧光在临床免疫诊断中的应用可能性]

[Possibilities of immunofluorescence in clinico-immunologic diagnosis].

作者信息

Storch W

出版信息

Z Gesamte Inn Med. 1983 Feb 15;38(4):104-6.

PMID:6344463
Abstract

The immunofluorescence still represents the essential method of the proof of antibodies circulating in the serum, which are of clinical interest as diagnostic markers of autoimmune diseases. The consideration of subtypes of antibodies (instance antimitochondrial antibodies) additionally alleviates the differential diagnosis. Newer methods of immunofluorescence, such as the double-immunofluorescence for the proof of antibodies against hormone-producing cells and against motorie end-plates, further the solid phase fluorescence immunoassay and the fluoroimmunocytoadherence will in future increasingly be used. Up to now the possibility was little used to use the antibodies circulating in our patients for the diagnosis of non-immunological diseases and the cell-biological diagnosis.

摘要

免疫荧光法仍然是检测血清中循环抗体的基本方法,这些抗体作为自身免疫性疾病的诊断标志物具有临床意义。对抗体亚型(如抗线粒体抗体)的研究有助于进一步进行鉴别诊断。免疫荧光的新方法,如用于检测抗激素产生细胞抗体和抗运动终板抗体的双免疫荧光法、固相荧光免疫测定法和荧光免疫细胞粘附法,未来将越来越多地被应用。到目前为止,利用患者体内循环抗体进行非免疫性疾病诊断和细胞生物学诊断的可能性很少被利用。

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