Drumtscheva M A, Todoroff D M, Stoinoff S G
Zentralbl Allg Pathol. 1983;127(1-2):119-24.
A simplified immunofluorescent morphometric technique for quantitative determination of immunoglobulin-forming cells (Ig-FC) in the small intestine mucosa was described. The following average values were established in 19 cases with chronic enteritis: total amount of Ig-FC: 117.5/0.1 mm2 villous area; IgA-FC = 78.4%, IgM-FC = 15.6%, and IgG-FC = 4.8%. An increased number of Ig-FC was found in a case with the syndrome of Peutz-Jeghers and in a case with alcoholic pancreatitis. Relatively high percentages of IgM-FC were established in two cases with long lasting chronic enterocolitis. The immunofluorescent study was performed simultaneously with the routine histology on the same biopsy specimens.
描述了一种用于定量测定小肠黏膜中免疫球蛋白形成细胞（Ig-FC）的简化免疫荧光形态计量技术。在19例慢性肠炎患者中确定了以下平均值：Ig-FC总量：每0.1平方毫米绒毛面积117.5个；IgA-FC = 78.4%，IgM-FC = 15.6%，IgG-FC = 4.8%。在1例Peutz-Jeghers综合征患者和1例酒精性胰腺炎患者中发现Ig-FC数量增加。在2例长期慢性小肠结肠炎患者中确定了相对较高百分比的IgM-FC。免疫荧光研究与常规组织学检查同时在相同的活检标本上进行。
