肾素在猪垂体前叶中的亚细胞分布。
The subcellular distribution of renin in hog anterior pituitary.
作者信息
Grammer R T, Naruse M, Inagami T
出版信息
Endocrinology. 1983 Jul;113(1):344-7. doi: 10.1210/endo-113-1-344.
PMID:6345143
Abstract
Renin in hog anterior pituitary was found to be located principally in the particulate fractions. Density gradient centrifugation of the granular fraction revealed a discrete band of renin activity distinct from lysosomal and mitochondrial markers. This band has a density similar to that of known kidney renin secretory granules and may be due to renin secretory or storage granules in the anterior pituitary.
摘要
研究发现，猪脑垂体前叶中的肾素主要位于颗粒部分。对颗粒部分进行密度梯度离心后，发现了一条与溶酶体和线粒体标记物不同的肾素活性离散带。这条带的密度与已知的肾脏肾素分泌颗粒相似，可能是由于垂体前叶中的肾素分泌或储存颗粒所致。
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