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克雅氏病:一组11例患者的临床、脑电图及神经病理学表现

Creutzfeld-Jakob disease: clinical, EEG and neuropathological findings in a cluster of eleven patients.

作者信息

Lechi A, Tedeschi F, Mancia D, Pietrini V, Tagliavini F, Terzano M G, Trabattoni G

出版信息

Ital J Neurol Sci. 1983 Apr;4(1):47-59. doi: 10.1007/BF02043437.

Abstract

10 of 11 Creutzfeld-Jakob disease patients were seen between February 1975 and November 1979. Whilst the clinical and EEG findings were uniform, the neuropathological changes were not: astrogliosis was always diffuse and widespread but the other typical changes (neuronal loss and spongiosis) varied greatly both in degree and location.

摘要

1975年2月至1979年11月期间,诊治了11例克雅氏病患者中的10例。虽然临床和脑电图检查结果一致,但神经病理学变化却并非如此:星形胶质细胞增生总是弥漫性且广泛存在的,但其他典型变化(神经元丧失和海绵状变性)在程度和位置上差异很大。

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