Fox R W, Samaan S S, Lockey R F, Bukantz S C
J Asthma. 1983;20(3):177-81. doi: 10.3109/02770908309114941.
Fifty clinically stable patients with asthma on maintenance theophylline therapy, mean dose of 15 mg kg-1 per day, were switched to an equivalent dose (X 1.56) of oxtriphylline SA for seven doses. All subjects remained clinically stable after the change during the study period. Oxtriphylline SA appears to be useful for the maintenance treatment of asthma and can be safely substituted for other theophylline maintenance regimens.
五十名临床症状稳定、正在接受氨茶碱维持治疗（平均每日剂量为15毫克/千克）的哮喘患者，被换用等效剂量（乘以1.56）的长效羟丙茶碱治疗七剂。在研究期间，所有受试者在换药后临床症状仍保持稳定。长效羟丙茶碱似乎对哮喘维持治疗有用，并且可以安全地替代其他氨茶碱维持治疗方案。
