Vroemen J P, van der Vliet J A, Kootstra G
Neth J Surg. 1983 May;35(2):55-60.
It is current practice to only consider heart-beating donors as suitable for organ donation. Patients who have sustained a permanent cardiac arrest are believed to be unsuitable for kidney retrieval, in the knowledge that the kidneys will have received extensive ischemic damage. In situ kidney preservation (ISP), using the double balloon triple lumen (DBTL) catheter, offers the possibility of harvesting valuable kidneys from these, otherwise unsuitable, donors. With this technique human kidneys can be cooled in situ prior to the donor nephrectomy. During ISP, nephrectomy can be performed under optimal surgical conditions. In this report indications for ISP, insertion technique of the DBTL catheter, legal aspects, and transplantation outcome of kidneys harvested by means of ISP are discussed.
目前的做法是仅将心跳型供体视为适合器官捐赠的对象。人们认为,经历过永久性心脏骤停的患者不适合进行肾脏摘取,因为已知肾脏会遭受广泛的缺血性损伤。使用双气囊三腔(DBTL)导管进行原位肾脏保存(ISP),为从这些原本不适合的供体获取有价值的肾脏提供了可能性。通过这种技术,在供体肾切除术前可在原位冷却人体肾脏。在ISP过程中,肾切除术可在最佳手术条件下进行。本报告讨论了ISP的适应证、DBTL导管的插入技术、法律问题以及通过ISP获取的肾脏的移植结果。