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[急性放射病肠型大鼠小肠中的蛋白水解过程]

[Proteolytic processes in the small intestine of rats with the intestinal form of acute radiation sickness].

作者信息

Nesterenko V S

出版信息

Radiobiologiia. 1983 May-Jun;23(3):379-81.

PMID:6346384
Abstract

It was shown that on the 3d day after total-body irradiation of rats (12 Gy), cathepsin "D" activity was increased and the processes of autolysis and proteolysis accelerated in the small intestine under the effect of trypsin. Extracts of the small intestine tissues increased the permeability of vessels. Ligation of the common bile duct lengthened the lifespan of irradiated animals and decreased the processes of proteolysis and the vessel permeability in the small intestine wall.

摘要

结果表明,大鼠全身照射(12戈瑞)后第3天,组织蛋白酶“D”活性增加,在胰蛋白酶的作用下小肠中的自溶和蛋白水解过程加速。小肠组织提取物增加了血管通透性。结扎胆总管可延长受照射动物的寿命,并减少小肠壁中的蛋白水解过程和血管通透性。

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