Orlowski W, Freedman P D, Lumerman H
Cancer. 1983 Sep 1;52(5):904-8. doi: 10.1002/1097-0142(19830901)52:5<904::aid-cncr2820520527>3.0.co;2-h.
A case of proliferative myositis of the masseter muscle in a 62-year-old woman is presented and pertinent literature is reviewed. This benign pseudosarcomatous proliferative lesion has not been previously reported in any of the muscles of mastication. Clinically the patient presented with pain and difficulty in opening of the mouth. On initial examination, a malignant salivary gland tumor was suspected. The proliferative myositis exhibits a disturbing microscopic appearance characterized by the presence of numerous hyperchromatic fibroblasts and oval or spindle-shaped giant cells which resemble malignant rhabdomyoblasts. These lesions have been often misdiagnosed as rhabdomyosarcoma and other types of sarcomas. Awareness of the microscopic characteristics of proliferative myositis and the possibility of its occurrence in the perioral soft tissues is important in avoiding misdiagnosis of this benign condition.
本文报告了一例62岁女性咬肌增生性肌炎的病例，并对相关文献进行了综述。这种良性假肉瘤性增生性病变此前尚未在任何咀嚼肌中报道过。临床上，患者表现为疼痛和张口困难。初步检查时，怀疑为恶性唾液腺肿瘤。增生性肌炎在显微镜下呈现出一种令人不安的外观，其特征是存在大量深染的成纤维细胞以及类似恶性横纹肌母细胞的椭圆形或梭形巨细胞。这些病变常被误诊为横纹肌肉瘤和其他类型的肉瘤。认识增生性肌炎的微观特征及其在口周软组织中发生的可能性，对于避免误诊这种良性疾病至关重要。
