Gallagher N D
Clin Gastroenterol. 1983 May;12(2):437-41.
The risk of developing folate deficiency is greatest in patients who have a poor diet and malabsorption secondary to disease of the jejunal mucosa or drugs which interfere with its metabolism. In contrast to cobalamin deficiency, in which body stores delay the onset of major metabolic complications, folate deficiency may develop in a matter of months. It is frequently possible to predict these deficiencies and always possible to reverse them by supplementation.
饮食不良以及因空肠黏膜疾病或干扰其代谢的药物导致吸收不良的患者发生叶酸缺乏的风险最高。与钴胺素缺乏不同，钴胺素缺乏时身体储备会延迟主要代谢并发症的发生，而叶酸缺乏可能在数月内就会出现。通常可以预测这些缺乏情况，并且总是可以通过补充来纠正。
