Mirouze J, Schmouker Y
Nouv Presse Med. 1978 Jan 28;7(4):261-3.
Twenty-five children born of 23 diabetic mothers, 17 of whom were treated with insulin, underwent glucose tolerance tests with estimation of blood insulin levels. These tests were performed on a regular basis before the age of five years, then every two years. Blood glucose and insulin disturbances were slight but appeared frequently since they were present in 56% of our cases. Our data show that blood glucose disturbances in children of diabetic mothers are more common if the diabetes of the mother suggests a maturity onset type on the basis of accompanying symptoms and treatment, and hence not insulin dependent. In this case, the chances that the child will become diabetic are much greater and this may be detected very early by a minor disturbance in the oral glucose tolerance test.
23位糖尿病母亲所生的25名儿童接受了葡萄糖耐量测试并测定了血胰岛素水平，其中17名母亲接受了胰岛素治疗。这些测试在儿童5岁前定期进行，之后每两年进行一次。血糖和胰岛素紊乱情况轻微，但出现频率较高，因为在我们56%的病例中都存在这种情况。我们的数据表明，如果母亲的糖尿病根据伴随症状和治疗提示为成年发病型，即非胰岛素依赖型，那么糖尿病母亲的孩子出现血糖紊乱的情况更为常见。在这种情况下，孩子患糖尿病的几率要大得多，并且通过口服葡萄糖耐量测试中的轻微紊乱可能会很早就检测出来。
