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经辐照的网状细胞肉瘤细胞对SJL小鼠IgE抗体反应的抑制作用

Suppression of IgE antibody response by irradiated reticulum cell sarcoma cells in SJL mice.

作者信息

Watanabe N, Ovary Z

出版信息

Int Arch Allergy Appl Immunol. 1983;72(1):6-8. doi: 10.1159/000234832.

Abstract

A low number of highly irradiated spleen or lymph node cells from reticulum cell sarcoma (RCS)-bearing SJL mice brings about suppression of IgE antibody production in adequately immunized and sublethally irradiated recipients, probably by known proliferative action of RCS cells on the few Ly-1 T cells which escaped from the irradiation.

摘要

来自患有网状细胞肉瘤(RCS)的SJL小鼠的少量高度辐射的脾脏或淋巴结细胞,会抑制经过充分免疫和亚致死剂量辐射的受体中IgE抗体的产生,这可能是由于RCS细胞对少数未受辐射影响的Ly-1 T细胞的已知增殖作用所致。

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