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肾移植术后晚期高血压的患病率及病因

Prevalence and causes of hypertension late after renal transplantation.

作者信息

Wauthier M, Vereerstraeten P, Pirson Y, Toussaint C, Alexandre G P, Kinnaert P, Van Geertruyden H, van Ypersele de Strihou C

出版信息

Proc Eur Dial Transplant Assoc. 1983;19:566-71.

PMID:6348753
Abstract

We analysed the prevalence and causes of hypertension in 77 patients followed greater than or equal to 7 years after renal transplantation. Prevalence of hypertension remains stable, around 55 per cent, up to 11 years post-transplant. Age, sex, type of original nephropathy, graft source or prednisolone dosage are not related to hypertension; body weight is greater in hypertensive patients. Presence of native kidneys is responsible for hypertension in about one-quarter of non-nephrectomised patients. No renal artery stenosis was observed in this group. At seven years, serum creatinine is greater in hypertensive patients, suggesting that graft dysfunction is an important cause of hypertension in long term survivors.

摘要

我们分析了77例肾移植术后随访时间大于或等于7年患者的高血压患病率及病因。移植后长达11年,高血压患病率保持稳定,约为55%。年龄、性别、原发病肾病类型、移植物来源或泼尼松龙剂量与高血压无关;高血压患者体重更大。约四分之一未行肾切除术的患者,其高血压由自身肾脏导致。该组未观察到肾动脉狭窄。7年时,高血压患者的血清肌酐更高,提示移植物功能障碍是长期存活者高血压的重要原因。

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