Hughes K S, Marrangoni A G, Thompson D R, Turbiner E
Radiology. 1983 Sep;148(3):823-6. doi: 10.1148/radiology.148.3.6348871.
Hepatobiliary scans were obtained with Tc-99m-disofenin in 15 dogs. Of these, 5 served as controls, 5 were infused with E. coli endotoxin for 4 hours (endotoxic shock group), and 5 were bled to a mean pressure similar to that of the endotoxic shock group (hemorrhagic shock group). Scans of the controls and hemorrhagic shock group were identical. Scans of the endotoxic shock group were markedly abnormal, with a prolonged hepatic phase and little excretion of isotope into the biliary tract, a pattern characteristic of mechanical obstruction of the common bile duct. These results should alert the clinician to the potential danger of abnormal hepatobiliary scans in the septic patient.
对15只犬进行了99m锝 - 二乙三胺五醋酸肝胆扫描。其中，5只作为对照，5只输注大肠杆菌内毒素4小时（内毒素休克组），5只放血至与内毒素休克组相似的平均血压水平（失血性休克组）。对照组和失血性休克组的扫描结果相同。内毒素休克组的扫描结果明显异常，肝期延长，同位素很少排入胆道，这是胆总管机械性梗阻的典型表现。这些结果应提醒临床医生注意脓毒症患者肝胆扫描异常的潜在危险。
