Kobilková J, Jandová A, Motlík K, Coupek J, Heyberger K
Acta Cytol. 1983 Jul-Aug;27(4):417-20.
Raised leukocyte adherence inhibition (LAI) test values were found for 25 women with endometrial carcinoma and 12 women with benign hyperplastic endometrium. Of 42 patients with oligomenorrheic and polymenorrheic disturbances of the menstrual cycle and whose hyperestrogenism was assessed by cytologic indices (i.e., eosinophilic and karyopyknotic indices), 38 exhibited positive or borderline LAI test values with either one or both of the antigens used. The LAI test was negative with both antigens in four women with hyperestrogenism associated with a 28-day menstrual cycle. The high correlation between hyperestrogenism and positive LAI test results as well as between the LAI test and the presence of tumors suggests that both hormonal cytology and the LAI test might be useful as screening methods for evaluating risk factors for the development of malignant tumors of the female reproductive tract. Both methods are fairly simple, reproducible and convenient for long-term follow-up.
在25例子宫内膜癌患者和12例良性增生性子宫内膜患者中发现白细胞黏附抑制（LAI）试验值升高。在42例月经周期为月经过少和月经过多紊乱且通过细胞学指标（即嗜酸性和核固缩指标）评估为雌激素过多的患者中，38例使用一种或两种抗原时LAI试验值呈阳性或临界值。4例雌激素过多且月经周期为28天的女性使用两种抗原时LAI试验均为阴性。雌激素过多与LAI试验阳性结果之间以及LAI试验与肿瘤存在之间的高度相关性表明，激素细胞学和LAI试验都可能作为评估女性生殖道恶性肿瘤发生风险因素的筛查方法。这两种方法都相当简单、可重复，并且便于长期随访。
