van Dam-Mieras M C, Hemker H C
Haemostasis. 1983;13(3):201-8. doi: 10.1159/000214728.
A short review about the place of coagulation factor VII in the initial phase of blood coagulation is given. A theoretical model describing the relationship between the half-life times of vitamin K-dependent coagulation factors and the control frequency of oral anti-coagulation therapy is presented. The constraints that control frequency imposes on the type of determination to be carried out are discussed.