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Half-life time and control frequency of vitamin K-dependent Coagulation factors. Theoretical considerations on the place of factor VII in the control of oral anticoagulation therapy.

作者信息

van Dam-Mieras M C, Hemker H C

出版信息

Haemostasis. 1983;13(3):201-8. doi: 10.1159/000214728.

Abstract

A short review about the place of coagulation factor VII in the initial phase of blood coagulation is given. A theoretical model describing the relationship between the half-life times of vitamin K-dependent coagulation factors and the control frequency of oral anti-coagulation therapy is presented. The constraints that control frequency imposes on the type of determination to be carried out are discussed.

摘要

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