大疱性类天疱疮与多种自身免疫性疾病。一名患者同时患有普秃、大疱性类天疱疮、甲状腺功能减退、类风湿关节炎和中性粒细胞减少症。

Bullous pemphigoid and multiple autoimmune diseases. Alopecia universalis, bullous pemphigoid, hypothyroidism, rheumatoid arthritis, and neutropenia in one patient.

作者信息

Lynfield Y L, Green K, Gopal R

出版信息

J Am Acad Dermatol. 1983 Aug;9(2):257-61. doi: 10.1016/s0190-9622(83)80358-2.

Abstract

A 57-year-old white man developed Hashimoto's thyroiditis, bullous pemphigoid, and autoimmune neutropenia during the last year of his life. In addition, he had alopecia universalis since the age of 21 and rheumatoid arthritis since the age of 38. This unique constellation of autoimmune diseases has not been reported previously. Its significance is discussed in relation to the polyglandular failure syndrome and thymoma-related autoimmune disease.

摘要

一名57岁的白人男性在其生命的最后一年患上了桥本甲状腺炎、大疱性类天疱疮和自身免疫性中性粒细胞减少症。此外，他自21岁起就患有全秃，自38岁起患有类风湿性关节炎。这种独特的自身免疫性疾病组合此前尚未见报道。本文结合多腺体功能衰竭综合征和胸腺瘤相关自身免疫性疾病对其意义进行了讨论。