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不同尿激酶制剂的比较研究

Comparative study of different urokinase preparations.

作者信息

Millar W T, Smith J F

出版信息

Thromb Res. 1983 Jun 1;30(5):425-9. doi: 10.1016/0049-3848(83)90176-7.

Abstract

Three different urokinase preparations were assayed for amidolytic and plasminogen activator activity. It was found that the preparation with the least amidolytic activity displayed a significantly greater plasminogen activator activity than the others. These results suggest that this particular preparation may be more effective clinically and that the use of assay systems for the comparison of urokinase preparations must be treated with caution.

摘要

对三种不同的尿激酶制剂进行了酰胺水解活性和纤溶酶原激活剂活性测定。结果发现,酰胺水解活性最低的制剂显示出比其他制剂显著更高的纤溶酶原激活剂活性。这些结果表明,这种特定的制剂在临床上可能更有效,并且在使用测定系统比较尿激酶制剂时必须谨慎对待。

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