O'Connor M, Snover D C
Am Surg. 1983 Jul;49(7):379-84.
Tumors of adipose differentiation demonstrate considerable histologic variability as well as a wide variation in behavior patterns. A variety of clinical, gross, and microscopic features are useful in predicting behavior. Unfortunately, a number of different classification systems for liposarcoma with confusing nomenclature appear in the literature. This paper reviews general features affecting prognosis and presents a summary of the major classification systems. A subclassification of tumors into three grades (high, intermediate, and low) is suggested, based on potential for malignant behavior. Our system of grading may be used to guide the surgeon in the course of therapy. In light of the potential for confusion in identification and classification, good communication between surgeon and pathologist is essential to choice of appropriate therapy and ensuing chances for recurrence or survival.
脂肪分化肿瘤表现出相当大的组织学变异性以及行为模式的广泛差异。多种临床、大体和微观特征有助于预测其行为。不幸的是，文献中出现了一些用于脂肪肉瘤的不同分类系统，其命名令人困惑。本文回顾了影响预后的一般特征，并总结了主要的分类系统。基于恶性行为的可能性，建议将肿瘤细分为三个级别（高、中、低）。我们的分级系统可用于指导外科医生进行治疗。鉴于在识别和分类中可能存在混淆，外科医生和病理学家之间的良好沟通对于选择合适的治疗方法以及随之而来的复发或生存机会至关重要。
