Stubbe I, Gustafson A, Nilsson-Ehle P, Agren B
Arch Phys Med Rehabil. 1983 Sep;64(9):396-401.
The authors evaluated physiologic, psychologic and metabolic effects of a nine-week in-hospital training program on 14 men with severe disabling angina pectoris. The exercise program consisted of intensive interval training on an ergometer bicycle for two 30 min sessions daily. The physical performance increased by about 40% (p less than 0.001). Plasma insulin levels were reduced and glucose tolerance improved significantly. There was a decrease in plasma triglyceride and low-density lipoprotein (LDL) cholesterol levels, but no change in high-density lipoprotein (HDL) cholesterol, apolipoprotein AI and B concentrations. Plasma triglyceride (p less than 0.05) and LDL cholesterol (p less than 0.05) levels remained low three weeks after completion of the training period and the physical performance remained improved (p less than 0.01) even six months post-training. Four of the patients who had been disabled for at least five months were able to return to work. The authors suggest that comparatively short and intensive in-hospital rehabilitation of patients with coronary heart disease may be an attractive alternative to prolonged training on an outpatient basis, especially in patients with severe angina pectoris.
作者评估了一项为期九周的住院培训计划对14名重度致残性心绞痛男性患者的生理、心理和代谢影响。该运动计划包括每天在测力计自行车上进行两次30分钟的强化间歇训练。体能提高了约40%（p<0.001）。血浆胰岛素水平降低，葡萄糖耐量显著改善。血浆甘油三酯和低密度脂蛋白（LDL）胆固醇水平降低，但高密度脂蛋白（HDL）胆固醇、载脂蛋白AI和B浓度无变化。训练期结束三周后，血浆甘油三酯（p<0.05）和LDL胆固醇（p<0.05）水平仍保持较低，甚至在训练后六个月，体能仍保持改善（p<0.01）。14名患者中有4名至少已残疾五个月，现已能够重返工作岗位。作者认为，对于冠心病患者而言，相对短期且强化的住院康复治疗可能是门诊长期训练的一个有吸引力的替代方案，尤其是对于重度心绞痛患者。
