血清转钴胺素水平作为移植后骨髓植入的早期指标。
Serum transcobalamin levels as an early indicator of bone marrow engraftment following transplantation.
作者信息
Naparstek E, Rachmilewitz B, Rachmilewitz M, Fuks Z, Slavin S
出版信息
Br J Haematol. 1983 Oct;55(2):229-34. doi: 10.1111/j.1365-2141.1983.tb01242.x.
Abstract
Three B12 binding proteins, the transcobalamins TCI, TCII and TCIII, were determined serially in the serum of five patients who underwent bone marrow transplantation. The increase in TCII, followed by the increase in TCI, proved to be an early indicator of bone marrow regeneration, reaching a peak of up to twice its normal levels at least 5 d prior to the rise of the peripheral white blood cell count.
摘要
在五名接受骨髓移植的患者血清中，连续测定了三种维生素B12结合蛋白，即转钴胺素I（TCI）、转钴胺素II（TCII）和转钴胺素III（TCIII）。结果表明，TCII先升高，随后TCI升高，这是骨髓再生的早期指标，在外周血白细胞计数升高前至少5天，其水平达到正常水平的两倍之多。
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