Novoseler M A
Biofizika. 1983 Jul-Aug;28(4):570-2.
Studies were carried out of circular dichroism spectra of the complexes between poly-l-lysine (PL) and calf thymus DNA, E. coli DNA, T2--and T7--phage DNA, Modiolus sp. DNA. The results indicate that PL more strongly changes AT--DNA conformation as compared to GC DNA conformation. This change correlates with the size of minimal PL clusters on DNA investigated. Sequence of DNA bases produces almost no effect on conformational changes caused by the complex-formation with PL.
对聚-L-赖氨酸(PL)与小牛胸腺DNA、大肠杆菌DNA、T2和T7噬菌体DNA、贻贝属DNA之间形成的复合物的圆二色光谱进行了研究。结果表明,与GC DNA构象相比,PL更强烈地改变AT-DNA构象。这种变化与所研究的DNA上最小PL簇的大小相关。DNA碱基序列对与PL形成复合物所引起的构象变化几乎没有影响。