核糖体上鸟苷四磷酸和五磷酸的模板非依赖性合成。
Template-independent synthesis of guanosine tetra- and pentaphosphates on ribosomes.
作者信息
Belitsina N V, Klyachko E V, Shakulov R S
出版信息
FEBS Lett. 1983 Oct 3;162(1):39-42. doi: 10.1016/0014-5793(83)81044-8.
PMID:6352335
Abstract
It is shown that Escherichia coli ribosomes carrying poly(Lys)-tRNA can form (p)ppGpp in the presence of stringent factor in the absence of the poly(A) template. Template-independent synthesis of (p)ppGpp is suppressed by tetracycline and partially decreases if deacylated tRNA is omitted.
摘要
结果表明，携带聚赖氨酸 - tRNA的大肠杆菌核糖体在缺乏聚腺苷酸模板且存在严谨因子的情况下能够形成（p）ppGpp。（p）ppGpp的非模板依赖性合成受到四环素的抑制，并且如果省略去酰化tRNA则会部分降低。
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