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The pharmacology and clinical use of methotrexate.

作者信息

Jolivet J, Cowan K H, Curt G A, Clendeninn N J, Chabner B A

出版信息

N Engl J Med. 1983 Nov 3;309(18):1094-104. doi: 10.1056/NEJM198311033091805.

DOI:10.1056/NEJM198311033091805
PMID:6353235
Abstract
摘要

相似文献

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The pharmacology and clinical use of methotrexate.甲氨蝶呤的药理学与临床应用。
N Engl J Med. 1983 Nov 3;309(18):1094-104. doi: 10.1056/NEJM198311033091805.
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Biochemical and pharmacologic rationale for high-dose methotrexate.高剂量甲氨蝶呤的生化及药理学原理
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4
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
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Intrinsic resistance to methotrexate of cultured mammalian cells in relation to the inhibition kinetics of their dihydrololate reductases.培养的哺乳动物细胞对甲氨蝶呤的内在抗性与其二氢叶酸还原酶的抑制动力学的关系。
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Toward improved selectivity in cancer chemotherapy: the Richard and Hinda Rosenthal Foundation Award Lecture.迈向癌症化疗中更高的选择性：理查德与欣达·罗森塔尔基金会奖讲座
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7
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.对甲氨蝶呤耐药的人淋巴瘤和骨肉瘤细胞中对抗叶酸药物三甲曲沙、美托普林、高叶酸和CB3717的交叉耐药模式。
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8
Methotrexate, folate and the brain.
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Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.胸苷酸合成酶作为甲氨蝶呤敏感和耐药的人头颈癌及白血病细胞系中生长抑制的靶点。
Oncol Res. 1997;9(3):139-47.
10
Letter: Encephalopathy following CNS prophylaxis in childhood lymphoblastic leukemia.
Pediatrics. 1974 Jul;54(1):120-1.

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