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婴儿期低肾素性低醛固酮血症

Hyporeninemic hypoaldosteronism in infancy.

作者信息

Monnens L, Fiselier T, Bos B, van Munster P

出版信息

Nephron. 1983;35(2):140-2. doi: 10.1159/000183063.

DOI:10.1159/000183063
PMID:6353255
Abstract

Hyporeninemic hypoaldosteronism was observed in an infant at the age of 3 months. Persistent hyperkalemia, hyperchloremic acidosis and salt wasting were present. All abnormal electrolyte values were corrected by the administration of fludrocortisone. Both active and inactive renin were lowered. This infant had also an unexplained spastic quadriplegia and psychomotor retardation. Hyporeninemic hypoaldosteronism should be considered to be one of the causes of salt-losing in infancy.

摘要

在一名3个月大的婴儿中观察到低肾素性低醛固酮血症。存在持续性高钾血症、高氯性酸中毒和失盐。通过给予氟氢可的松,所有异常的电解质值均得到纠正。活性肾素和非活性肾素均降低。该婴儿还患有无法解释的痉挛性四肢瘫痪和精神运动发育迟缓。低肾素性低醛固酮血症应被视为婴儿失盐的原因之一。

相似文献

1
Hyporeninemic hypoaldosteronism in infancy.婴儿期低肾素性低醛固酮血症
Nephron. 1983;35(2):140-2. doi: 10.1159/000183063.
2
Amelioration of metabolic acidosis with fludrocortisone therapy in hyporeninemic hypoaldosteronism.氟氢可的松治疗低肾素性低醛固酮血症改善代谢性酸中毒
N Engl J Med. 1977 Sep 15;297(11):576-83. doi: 10.1056/NEJM197709152971104.
3
[Hyporeninemic hypoaldosteronism and the differential diagnosis of hyperkalemia].[低肾素性低醛固酮血症与高钾血症的鉴别诊断]
Schweiz Med Wochenschr. 1982 Dec 4;112(49):1764-74.
4
Hyporeninemic hypoaldosteronism.低肾素性低醛固酮血症
Adv Intern Med. 1979;24:385-405.
5
Hyperkalemia due to selective hypoaldosteronism.选择性醛固酮缺乏症所致高钾血症
South Med J. 1977 May;70(5):634-6. doi: 10.1097/00007611-197705000-00044.
6
Hyporeninemic hypoaldosteronism associated with acquired immune deficiency syndrome.与获得性免疫缺陷综合征相关的低肾素性低醛固酮血症
Am J Med. 1987 May;82(5):1035-8. doi: 10.1016/0002-9343(87)90171-9.
7
Hyporeninemic hypoaldosteronism, sodium wasting and mineralocorticoid-resistant hyperkalemia in two patients with obstructive uropathy.两名梗阻性尿路病患者出现低肾素性低醛固酮血症、失钠及盐皮质激素抵抗性高钾血症。
Am J Nephrol. 1983 Jul-Aug;3(4):223-7. doi: 10.1159/000166717.
8
Evaluating renin and aldosterone levels in children with organic acidemia-therapeutic experience with fludrocortisone.评估有机酸血症患儿的肾素和醛固酮水平-氟氢可的松的治疗经验。
Eur J Pediatr. 2023 Dec;182(12):5447-5453. doi: 10.1007/s00431-023-05221-8. Epub 2023 Sep 29.
9
Calcineurin inhibitor-related hyperkalemia is caused by hyporeninemic hypoaldosteronism and fludrocortisone is an effective treatment: Report of a case series and review of the literature.钙调磷酸酶抑制剂相关性高钾血症是由于低肾素-低醛固酮血症引起的,氟氢可的松是一种有效的治疗药物:病例系列报告及文献复习。
Pediatr Transplant. 2024 Jun;28(4):e14778. doi: 10.1111/petr.14778.
10
[Hyporeninemic hypoaldosteronism. Case report and attempt at pathophysiological classification (author's transl)].[低肾素性低醛固酮血症。病例报告及病理生理分类尝试(作者译)]
Med Clin (Barc). 1980 Nov 10;75(8):342-5.

引用本文的文献

1
Hyporeninemic hypoaldosteronism in RMND1-related mitochondrial disease.与 RMND1 相关的线粒体疾病中的低肾素血症性低醛固酮血症。
Pediatr Nephrol. 2024 Jan;39(1):125-129. doi: 10.1007/s00467-023-06079-6. Epub 2023 Jul 14.
2
Nephrogenic Syndrome of Inappropriate Antidiuresis Mimicking Hyporeninemic Hypoaldosteronism: Case Report of Two Infants.模仿低肾素性低醛固酮血症的肾源性抗利尿激素分泌异常综合征:两例婴儿病例报告
J Clin Res Pediatr Endocrinol. 2023 May 29;15(2):214-219. doi: 10.4274/jcrpe.galenos.2021.2021.0191. Epub 2021 Oct 14.
3
Renal tubular hyperkalaemia in childhood.
儿童肾小管性高钾血症
Pediatr Nephrol. 1988 Oct;2(4):498-509. doi: 10.1007/BF00853448.