Weissmann H S, Byun K J, Freeman L M
Semin Nucl Med. 1983 Jul;13(3):199-222. doi: 10.1016/s0001-2998(83)80016-6.
Each year approximately 52 million Americans are injured, of which 11 million require hospitalization and 110,000 die. This has an associated health care cost of 3 billion dollars. Hepatobiliary injuries have always constituted a significant area of involvement. They have become more easily detectable since the advent of technetium-99m analogs of iminodiacetic acid (IDA). Biliary leakage secondary to other causes, such as inflammation, neoplasm, and iatrogenic factors are also well demonstrated in a safe, simple, and rapid manner with radionuclide imaging. The relatively low patient radiation dose that is associated with these procedures permits follow-up studies when necessary.