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[人尿中性α-葡萄糖苷酶的多态性]

[Polymorphism of neutral alpha glucosidase of human urine].

作者信息

Lavrenova T P, Lukomskaia I S

出版信息

Vopr Med Khim. 1983 Jul-Aug;29(4):91-5.

PMID:6353754
Abstract

Multiple forms of neutral alpha-glucosidase were found in human urine. In a number of individuals three enzyme forms were detected, in other persons--four forms. The alpha-glucosidase I and 2 were present in urine as well as in kidney of some individuals, whereas in urine of other persons only alpha-glucosidase I was found. Both forms of neutral alpha-glucosidase I and 2 from human urine exhibited the maximal activity at pH 5.75 = 6.5, had a similar Km value (0.73 mM) with maltose as a substrate and did not differ in their properties from the corresponding forms of neutral alpha-glucosidase in a soluble fraction from human kidney.

摘要

在人尿中发现了多种形式的中性α-葡萄糖苷酶。在一些个体中检测到三种酶形式,在其他个体中检测到四种形式。α-葡萄糖苷酶I和2存在于一些个体的尿液和肾脏中,而在其他个体的尿液中仅发现α-葡萄糖苷酶I。来自人尿的中性α-葡萄糖苷酶I和2的两种形式在pH 5.75 = 6.5时表现出最大活性,以麦芽糖为底物时具有相似的Km值(0.73 mM),并且它们的性质与来自人肾可溶性部分的相应形式的中性α-葡萄糖苷酶没有差异。

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