大鼠28S核糖体核糖核酸中α-肌动蛋白切割位点处核苷酸的序列。
The sequence of the nucleotides at the alpha-sarcin cleavage site in rat 28 S ribosomal ribonucleic acid.
作者信息
Chan Y L, Endo Y, Wool I G
出版信息
J Biol Chem. 1983 Nov 10;258(21):12768-70.
PMID:6355092
Abstract
The sequence of the 521 nucleotides at the 3' end of a rat 28 S rRNA gene was determined. The region encompasses the site of cleavage of 28 S rRNA by the cytotoxin alpha-sarcin. The toxin hydrolyzes a phosphodiester bond on the 3' side of a guanine residue 393 nucleotides from the 3' end. The alpha-sarcin domain is composed of a purine-rich sequence of 14 highly conserved nucleotides.
摘要
测定了大鼠28S rRNA基因3'端521个核苷酸的序列。该区域包含细胞毒素α-肌动蛋白切割28S rRNA的位点。该毒素水解3'端393个核苷酸处鸟嘌呤残基3'侧的磷酸二酯键。α-肌动蛋白结构域由14个高度保守的富含嘌呤的核苷酸序列组成。
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