King C T, Clark T D, Lovett J, Cash J B, Primus F J, McRoberts J W, Flanigan R C
J Urol. 1983 Nov;130(5):871-3. doi: 10.1016/s0022-5347(17)51543-8.
Specimens of transitional cell carcinoma of the ureter and renal pelvis from 20 patients were tested for blood group antigenicity using immunoperoxidase and specific red cell adherence methods. The results of antigen testing were correlated with tumor stage and grade as well as the subsequent clinical course of the patients. The specific red cell adherence test was negative in 80 per cent and the immunoperoxidase test was negative in 40 per cent of all tumors. Of the 4 patients with positive specific red cell adherence tests 3 had high grade (II to III), invasive tumors as did 7 of 12 with tumors that were positive by immunoperoxidase testing. Blood group antigen testing did not prove helpful in predicting the clinical course of our patients. In addition, a careful review of previously published data does not support the conclusion that blood group antigen testing is a valuable predictor of upper tract tumor aggressiveness.
采用免疫过氧化物酶法和特异性红细胞黏附法，对20例输尿管及肾盂移行细胞癌标本进行血型抗原性检测。抗原检测结果与肿瘤分期、分级以及患者后续临床病程相关。在所有肿瘤中，特异性红细胞黏附试验80%为阴性，免疫过氧化物酶试验40%为阴性。特异性红细胞黏附试验阳性的4例患者中，3例为高级别（II至III级）浸润性肿瘤；免疫过氧化物酶试验阳性的12例肿瘤患者中，7例为高级别浸润性肿瘤。血型抗原检测对预测患者的临床病程并无帮助。此外，对既往发表数据的仔细回顾并不支持血型抗原检测是上尿路肿瘤侵袭性的重要预测指标这一结论。
