Magnin P H, Casas J G, Duhm G
Med Cutan Ibero Lat Am. 1983;11(4):247-52.
Neurotropic melanoma is a variant of desmoplastic melanoma with a distinctive neural or Schwannian appearance of amelanotic spindled melanocytes. We report a 81 years old woman with a neurotropic melanoma on her left superciliary region. The lesion began as a lentigo maligna melanoma, Clark's level V, 4,08 mm. in thickness. The tumor relapsed on seven instances over a follow-up period of five years. Microscopic study showed a spindle cell pattern with marked neurotropism. Patient's general condition is good notwithstanding her evolution and relapses. This type of melanoma usually occurs on the face and, as we observed in our cases, exhibits a marked tendency for peripheral nerve invasion.
亲神经性黑色素瘤是促结缔组织增生性黑色素瘤的一种变体，其无黑色素的梭形黑素细胞具有独特的神经或雪旺氏外观。我们报告了一名81岁女性，其左眉上区域患有亲神经性黑色素瘤。该病变最初为恶性雀斑样黑色素瘤，克拉克分级为V级，厚度为4.08毫米。在五年的随访期内，肿瘤复发了七次。显微镜检查显示为梭形细胞模式，具有明显的亲神经性。尽管病情发展和复发，但患者的一般状况良好。这种类型的黑色素瘤通常发生在面部，正如我们在病例中观察到的，其表现出明显的侵犯周围神经的倾向。
