Owen W R, Wolfe I D, Burnett J W, Bruce W G
South Med J. 1978 Apr;71(4):477-9. doi: 10.1097/00007611-197804000-00040.
The cases of epithelioma cuniculatum in this report illustrate the unusual appearance and diagnostic difficulty of the lesion. Early diagnosis resulted in apparent cure with adequate local excision in some cases, whereas amputation was necessary for advanced or recurrent tumors. Distant metastasis may occur. Superficial biopsy specimens may yield inadequate tissue for proper diagnosis. Verrucous carcinoma should be considered as a diagnostic possibility in any atypical or recurrent "wart" on the sole.
本报告中的皮肤腺样上皮瘤病例说明了该病变不同寻常的外观及诊断难点。早期诊断在某些情况下通过充分的局部切除可实现明显治愈，而对于晚期或复发性肿瘤则需要截肢。可能会发生远处转移。浅表活检标本可能无法提供足够的组织用于准确诊断。对于足底任何非典型或复发性“疣”，都应考虑疣状癌的诊断可能性。
