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对献血者进行恶性疟原虫和三日疟原虫疟疾筛查。即用型同源抗原的应用。

Screening blood donors for Plasmodium falciparum malariae. Application of ready-to-use homologous antigens.

作者信息

Deroff P, Reguer M, Simitzis A M, Boudon A, Saleun J P

出版信息

Vox Sang. 1983;45(5):392-6. doi: 10.1111/j.1423-0410.1983.tb01933.x.

DOI:10.1111/j.1423-0410.1983.tb01933.x
PMID:6356590
Abstract

Prevention of post-transfusion malaria remains a worrying problem. Until now it was very difficult to obtain homologous antigens, and immunologic methods used to detect malaria were expensive. We tested the ready-to-use Plasmodium falciparum prepared slides using the IFA (indirect fluorescent antibody) test on 866 selected potentially dangerous donors and known malaria cases. We found that it is a simple, quick, reliable and inexpensive method that can be easily used by blood banks and improve blood transfusion safety.

摘要

预防输血后疟疾仍然是一个令人担忧的问题。直到现在,获取同源抗原非常困难,而且用于检测疟疾的免疫方法成本高昂。我们使用间接荧光抗体(IFA)试验,对866名选定的潜在危险献血者和已知疟疾病例,检测了即用型恶性疟原虫制备玻片。我们发现,这是一种简单、快速、可靠且廉价的方法,血库可轻松使用,从而提高输血安全性。

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