Szymanoski J, Baranowska B, Migdalska B, Kozlowicz I
J Urol Nephrol (Paris). 1976 Oct-Nov;82(10-11):827-36.
Using the radioimmunological method and applying the double antibody separation technique, testosterone was determined in 14 patients and LH in a few. A group of men in good health aged between 20 and 60 years (22 persons) was used as a control and a group of men aged from 60 to 90 years (24 persons) in whom the size of the prostate gland corresponded to their age. In 4 patients, testosterone levels were determined before and after prostatectomy. It was found that testosterone levels in the serum of men aged over 60, in good health, were markedly lower. Patients with prostatic hypertrophy showed testosterone concentrations several times higher than the men in the control groups. Testosterone levels in patients with considerable hypertrophy of the prostate were higher than in patients with moderate hypertrophy. Adenomectomy had a remarkable influence on the decrease of testosterone in the serum.
采用放射免疫法并应用双抗体分离技术，对14例患者的睾酮进行了测定，对少数患者测定了促黄体生成素（LH）。选取一组年龄在20至60岁之间的健康男性（22人）作为对照，另一组为年龄在60至90岁之间的男性（24人），其前列腺大小与年龄相符。对4例患者在前列腺切除术前和术后测定了睾酮水平。结果发现，60岁以上健康男性血清中的睾酮水平明显较低。前列腺肥大患者的睾酮浓度比对照组男性高出数倍。前列腺明显肥大患者的睾酮水平高于中度肥大患者。腺瘤切除术对血清睾酮的降低有显著影响。
