在高血压治疗中，对喷布洛尔与速尿联合用药及两药单独用药进行比较。
A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension.
作者信息
Chadha D R, Houtzagers J J
出版信息
Br J Clin Pharmacol. 1983 Nov;16(5):561-4. doi: 10.1111/j.1365-2125.1983.tb02217.x.
Abstract
Forty-one patients completed a randomized, double-blind, between-group comparison of a combination of penbutolol and frusemide, with penbutolol alone, and frusemide alone in the management of mild to moderate essential hypertension. The results suggest that the combination caused a superior reduction in systolic and diastolic pressure compared with penbutolol and a superior reduction in systolic blood pressure compared with frusemide.
摘要
41名患者完成了一项随机、双盲、组间对照试验，比较了喷布洛尔与速尿联合用药、单独使用喷布洛尔以及单独使用速尿治疗轻至中度原发性高血压的效果。结果表明，与单独使用喷布洛尔相比，联合用药能更显著地降低收缩压和舒张压；与单独使用速尿相比，联合用药能更显著地降低收缩压。
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3
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