Callegaro L, Denti E
Int J Artif Organs. 1983 Jul;6 Suppl 1:107-10.
The use of immobilized enzymes, antibodies or reactive proteins was recently considered as a promising approach for detoxification purposes. The appropriate solutions of some specific problems were described and discussed. An hollow fiber haemodialyzer with a membrane surface area of 0.6 m2 was used as standard support for L-asparaginase immobilization. Hemoperfusion columns based on modified agarose beads were also manufactured for the immobilization of antiphenobarbital antibodies.
固定化酶、抗体或反应性蛋白质的应用最近被认为是一种用于解毒目的的有前途的方法。文中描述并讨论了一些特定问题的适当解决方案。一种膜表面积为0.6平方米的中空纤维血液透析器被用作固定化L-天冬酰胺酶的标准载体。还制备了基于改性琼脂糖珠的血液灌流柱用于固定化抗苯巴比妥抗体。