[急性放射病初期白化大鼠肝脏中乙酰化辅酶的生物合成]
[Biosynthesis of the acetylation coenzyme in albino rat liver in the initial period of acute radiation sickness].
作者信息
Moĭseenok A G, Gurinovich V A, Ovchinnikov V A
出版信息
Radiobiologiia. 1983 Sep-Oct;23(5):680-2.
PMID:6359248
Abstract
Mature albino rats were exposed to gamma-rays in a sublethal dose. A decrease of 22-35%, 13-39% and 29-37% was observed in the incorporation of 14C-pantothenate, 4'-phosphopantetheine and CoA, respectively, into the extracted fraction of free vitamin. After the first hour of observation specific activity of CoA decreased by 33% and corresponded to a decrease in the activity of ATP: D-pantothenate-4'-phosphotransferase.
摘要
将成熟的白化大鼠暴露于亚致死剂量的γ射线中。观察到，分别加入到游离维生素提取部分中的14C-泛酸盐、4'-磷酸泛酰巯基乙胺和辅酶A的量减少了22 - 35%、13 - 39%和29 - 37%。在观察的第一个小时后，辅酶A的比活性降低了33%，这与ATP：D-泛酸盐-4'-磷酸转移酶活性的降低相对应。
相似文献
1
[Biosynthesis of the acetylation coenzyme in albino rat liver in the initial period of acute radiation sickness].[急性放射病初期白化大鼠肝脏中乙酰化辅酶的生物合成]
Radiobiologiia. 1983 Sep-Oct;23(5):680-2.
2
[Proteinase inhibitors of the blood plasma in the early period of the development of acute radiation sickness in monkeys].[猕猴急性放射病早期血浆中的蛋白酶抑制剂]
Radiobiologiia. 1987 Mar-Apr;27(2):250-3.
3
[Inhibition of phospholipase activity in liver mitochondria of gamma-irradiated rats].[γ射线照射大鼠肝脏线粒体中磷脂酶活性的抑制作用]
Radiobiologiia. 1985 Jul-Aug;25(4):551-3.
4
5
[Postradiation disorders in the adenine-phosphoribosyltransferase pathway of AMP biosynthesis].[AMP生物合成的腺嘌呤磷酸核糖基转移酶途径中的辐射后紊乱]
Radiobiologiia. 1984 May-Jun;24(3):347-50.
6
[Development of long-term radiation effects in rats after whole-body fractionated gamma-irradiation].[全身分次γ射线照射后大鼠长期辐射效应的发展]
Radiobiologiia. 1983 Nov-Dec;23(6):832-5.
7
[The proteinase activity in the cell nuclei of rats following exposure to gamma radiation and methylnitrosourea].[大鼠暴露于γ射线和甲基亚硝基脲后细胞核中的蛋白酶活性]
Radiobiologiia. 1990 May-Jun;30(3):312-6.
8
9
[Nucleoside mono- and nucleoside diphosphate kinase activities in rat liver and brain in radiation sickness].[辐射病大鼠肝脏和大脑中的核苷单磷酸激酶和核苷二磷酸激酶活性]
Ukr Biokhim Zh (1978). 1983 Jul-Aug;55(4):456-9.
Zotero 插件