Lymphoma after organ transplantation: radiologic manifestations in the central nervous system, thorax, and abdomen.

The radiographic findings of post-transplantation lymphoma in 15 patients are demonstrated. Variations in patterns from those of lymphomas in nonimmunosuppressed patients, etiologic factors, histologic features, and differential diagnosis are discussed. The common finding of central lucency of masses seen on CT scans correlated with necrosis seen at histologic examination. In the post-transplant patient, single or multiple masses, particularly if centrally lucent, should suggest post-transplantation lymphoma. Histologic proof with anatomic localization is important, however, to determine appropriate therapy.